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Opiates

What are opiates (Heroin)

Opiates can be divided into two groups: the naturally occurring opiates like heroin and morphine which are derived from the opium poppy and the synthetic opiates like methadone and dipipanone.

Drugs include:

Drug name

Brand/common name

Street name

Therapeutic dose range

Codeine Actifed
Phensedyl
Codeine
Linctus
Codis
   
Buprenorphine Temgesic Tems 0.6-1.6mg
Dextropropoxyphene Distalgesic
Co-proximol
   
Dextromoramide Palfium Palf, peach 5-10mg
Diamorphine Heroin Smack, H  
Dihydrocodeine DF118 DFs, diffs 120-180mg
Dipipanone Diconal Dikies 30mg
Methadone Physeptone Meth, phy 15-40mg
Morphine MST Continus
Kaolin and Morphine
Cyclimorph
   
Opium Gees Linctus    
Nubain Nalbuphine hydrochloride   1 ml vial
 

Street use

Opiates can be smoked, sniffed, inhaled or injected depending on the drug and preparation.

Drug effect

Opiates are used for their analgesic (painkilling) properties. They also reduce breathing rate and heart rate, hunger and anxiety. These effects combined with an increase in blood flow to the skin gives the warm, contented and sometimes euphoric feeling that is often reported. First time users may vomit but this stops with repeated use.

At low doses, opiates do not interfere with physical coordination or mental alertness. After high doses, opiates produce a stupor (gauching).

Dependency

Tolerance to opiates develops very quickly and after a few weeks of regular use, doses must be increased to produce the same effect.

Dependence takes longer to develop, but after taking opiates regularly for some months there are physical withdrawal symptoms. The speed with which dependence develops and the severity of withdrawal symptoms experienced depends upon the quantity and type of drug taken, the method of administration and to some extent the expectations of the user.

Withdrawal usually begins eight to 48 hours after the last dose of drug, peaks after three to five days and then fades after five to 14 days.

Withdrawal from opiates can be unpleasant and uncomfortable. Symptoms are similar to a bad bout of flu and include: sweating, stomach cramps, muscular pain, running nose and diarrhoea. Most symptoms fade fairly quickly but sleeplessness and feelings of weakness may continue for some months.

Long-term use

The physical effects of long-term opiate use are not often serious in themselves. Common side-effects include constipation, irregular periods (menstrual cycle) and weight loss. However the use of unsterile equipment and the injecting of adulterated heroin, crushed tablets or the contents of capsules, can lead to more serious problems, including abscesses, vein collapse, loss of limbs, hepatitis B and C and HIV infection.

Overdose risk

Deaths from opiate overdoses are relatively rare although the intravenous use of Diconal is particularly dangerous. The risk increases after a period of abstinence or when opiates are mixed with other drugs such as cocaine, barbiturates or alcohol.

Risks in pregnancy

Many women do not have periods (menstrual cycle) when they are using opiates regularly but as soon as they cut down or stop their periods return. Many female drug users become pregnant at this time.

There is no evidence that opiates cause birth defects although they may possibly increase the risk of miscarriage and still births. However, opiate use should not be stopped suddenly because this also increases the risk of miscarriage or premature labour. Gradual withdrawal over 12 weeks may be advised.

Babies born to mothers who continue to "use" throughout the pregnancy show withdrawal symptoms within three days of birth (possibly longer if the mother has been using methadone). Symptoms include excessive restlessness, shrill crying, sleeplessness, constant sucking, diarrhoea, yawning and sneezing. In severe cases babies may suffer convulsions which can be fatal.

Legal status

Opiates are prescription-only medicines and most are controlled drugs (Class A or B, Schedule 2) which means that it is an offence to possess or sell the drug without a prescription or authority. See individual drugs for further details.

 

Maximum penalty
For possession:


For dealing:

Class A
Seven years and/or
unlimited fine

Life and/or
unlimited fine

Class B
Five years and/or
unlimited fine

14 years and/or
unlimited fine

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Dipipanone and cyclizine (Diconal)

Street name

Dikes, Dikies

Brand name

Diconal (Calmic)

Drug effect

Painkiller and depressant ("downer") and anti-emetic (anti-sickness)

Description

Pink scored tablet (Dipipanone 10mg and Cyclizine 30mg)

Therapeutic use

Moderate to severe pain

Street use

By mouth or injecting crushed tablets

Dependency

Yes

Withdrawal

Effects of Diconal last for four to six hours. Withdrawal is similar to other opiates with flu-like symptoms lasting for five to 10 days.

Long-term use

Constipation
Breathing difficulties
Irregular periods (menstrual cycle)

If injected

- causes sudden drop in blood pressure which can be
  fatal
- circulatory problems and tissue damage caused by
  alkaline base of tablet
- septic abscesses from alkaline base of tablet
- infection risk.

Overdose risk

If Diconal is injected there is a serious risk of overdose because of loss of blood pressure. Many of the overdose deaths among opiate injectors involve this drug.

Go back to the table.

Dihydrocodeine (DF118)

Street name

DFs, Diffs

Brand name

DF118 (Duncan Flockhart), DHC Continus (Napp)

Drug effect

Painkiller and depressant ("downer")

Description

White tablets (30mg)
Elixir (10mg/5ml)
Ampoules (50mg/ml)

Therapeutic use

Moderate to severe pain

Street use

Mainly by mouth as drug does not dissolve in water. This makes it difficult to inject.

Dependency

Yes

Withdrawal

Probably similar to other opiates. Flu-like symptoms for five days.

Long-term use

Constipation
Breathing difficulties
Irregular periods (menstrual cycle)

Overdose risk

Probably fairly low, although risks increase if drug is mixed with other drugs.

Legal status

Dihydrocodeine is a Class B controlled drug (Schedule 2). This means it is an offence to possess the drug without a prescription or to supply it to others.

Medical practitioners are not required to notify the authorities about anyone they suspect to be dependent on this drug.

Maximum penalty
For possession: Five years and/or unlimited fine
For dealing:
14 years and/or unlimited fine

If prepared for injection the increased maximum penalties apply:

Maximum penalty

For possession: Seven years and/or unlimited fine

For dealing: Life and/or unlimited fine

Go back to the table.

Diamorphine (heroin)

Street name

Smack, H, Skag

Brand name

Diamorphine BP

Drug effect

Painkiller and depressant ("downer")

Description

White/brown powder normally containing five to 30 percent pure heroin. Often cut with adulterants or other drugs. Diamorphine BP - clear solution in ampoules. Also available 10mg tablet and 5, 10, 30, 100, 500mg freeze dried powder in ampoules.

Therapeutic use

Severe pain

Street use

Smoked, sniffed, "Chasing the Dragon" (inhaling fumes of heated heroin), injected. Heroin produces little effect if taken by mouth.

Dependency

Yes

Withdrawal

Effects of heroin last for two to three hours and withdrawal symptoms appear eight to 24 hours after last dose. Symptoms resemble severe flu together with diarrhoea. They peak around the third day and fade after five to ten days. Sleeplessness may continue for some months.

Long-term use

Constipation
Breathing difficulties
Irregular periods (menstrual cycle)

If injected

-infection risk
-circulatory problems.

Overdose risk

Deaths from the use of heroin alone are relatively infrequent. However the overdose risk increases after a period of abstinence or if heroin is mixed with drugs like cocaine, barbiturates or alcohol.

Legal status

Diamorphine is a prescription-only medicine and is a Class A controlled drug (Schedule 2). This means it is an offence to possess the drug without a prescription or to supply it to others.

Maximum penalty
For possession: Seven years and/or unlimited fine
For dealing: Life and/or unlimited fine

 

Go back to the table.

Methadone

Street name

Meth, Phy

Brand name

Physeptone (Calmic)

Drug effect

Painkiller and depressant ("downer")

Description

White scored tablet marked Welcome (5mg)
1ml ampoules (10mg/ml)
Mixture (1mg/1ml)
Linctus

Therapeutic use

Severe pain and opiate dependence

Street use

By mouth or injecting crushed tablets, linctus or ampoule

Dependency

Yes

Withdrawal

The effects of methadone last up to 24 hours which is longer than heroin. Withdrawal symptoms are slower to develop but last longer. Flu-like symptoms appear up to two days after last dose, peak after five to six days and fade after 14 days. Sleeplessness may last for longer. It has been suggested that withdrawal is more difficult than from heroin.

Long-term use

Constipation
Breathing difficulties
Irregular periods (menstrual cycle)

If injected

-infection risk
-circulatory problems.

Depresses effects of other opiates.

Overdose risk

Deaths from the use of methadone alone are relatively infrequent. However the overdose risk increases after a period of abstinence or if methadone is mixed with other drugs such as barbiturates or alcohol.

Legal status

Methadone is a prescription-only medicine and is a Class A controlled drug (Schedule 2). This means it is an offence to possess the drug without a prescription and to supply it to others.

Maximum penalty
For possession: Seven years and/or unlimited fine
For dealing:
Life and/or unlimited fine

For more detail information on Methadone please click here.

Go back to the table.

Buprenorphine (Temgesic)

Street name

Tems

Brand name

Temgesic (Reckitt and Colman)

Drug effect

Painkiller and depressant ("downer")

Description

White tablet (0.2mg) marked with symbol. White tablet (0.4mg) marked with symbol (dissolved under tongue). 1ml & 2ml ampoules (0.3mg/ml).

Therapeutic use

Moderate to severe pain

Street use

Dissolved in the mouth, crushed and sniffed or injected.

Dependency

Yes

Withdrawal

Effects of Temgesic last for about six hours. Withdrawal symptoms begin within a day of the last dose. Withdrawal symptoms include tightness of chest, headaches, dry retching and flu-like symptoms.

Long-term use

Constipation
Breathing difficulties
Irregular periods (menstrual cycle)

If injected

-infection risk
-circulatory problems.

Overdose risk

Overdose risk is probably low

Legal status

Temgesic is a prescription-only medicine and was recently made a controlled drug, Class C (Schedule 3).

Maximum penalty
For possession: Two years
For dealing:
Five years

SPECIAL NOTE

Temazepam (one of the benzodiazepines) is also sometimes called Tems and thus can be confused with Temgesic.

For more detailed inforamtion on Burenorphine (Subutex) please click here.

Go back to the table.

Nubain (Nalbuphine hydrochloride)

Street name

Nubain

Brand name

Nubain

Drug effect

Nubain is a potent analgesic (painkiller).

Description

Injection 10mg/ ml. Available on the black market in 2ml (20mg) multi close vial.

Therapeutic use

Moderate to severe pain

Street use

Injected

Dependency

Yes

Withdrawal

Similar to other opiates.
Abdominal cramps, anxiety, nausea and vomiting, crying, restlessness, irritability and "flu like" symptoms.

Long-term use

Considered to have low abuse potential, but physical, psychological dependence and tolerance may develop following long-term or misuse or abuse.

 

Overdose risk

Deaths from overdose are relatively rare, but complications associated with injecting, like hepatitis C or septicaemia, are more likely. Overdose may produce pinpoint pupils, sedation, dizziness and breathing difficulties. Its effects are increased if mixed with other central nervous system depressants such as tranquillisers, sedatives, hypnotics or alcohol.

Legal status

Nubain is not controlled under the Misuse of Drugs Act (1971). It is a prescription-only medicine.

SPECIAL NOTE

Nubain is abused particularly by people involved in competitive sports especially body builders to overcome musculo-skeletal pain despite the risk of injury, to keep calm before competition, and to take part in sport or training after injury.
Nubain addicts shoot up between six to eight times a day whereas heroin users would tend to shoot up only once. This carries considerable risk of infection, hepatitis C, HIV and other infections if sharing equipment.

Go back to the table.

Related topics

Drug Tests

The Detox Handbook

 
 
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Home Health UK is one of the UK’s leading suppliers of health tests for medical professionals the home and workplace. Our range of tests include drug testing kits, Chlamydia tests, oral saliva tests, pregnancy tests, ovulation tests, cholesterol tests, drug screening tests, home drug tests and DNA Paternity Tests.
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